1218795-44-8Relevant articles and documents
Synthesis of fused 4-Iodoselenophene[2,3-b]thiophenes by electrophilic cyclization of 3-alkynylthiophenes
Stein, Andre L.,Da Rocha, Juliana,Menezes, Paulo Henrique,Zeni, Gilson
experimental part, p. 705 - 710 (2010/03/24)
We present here our results on the electrophilic cyclization reaction of 3-alkynylthiophenes with different electrophiles such as I2, ICl, and PhSeBr. The cyclization reaction proceeded cleanly under mild reaction conditions, giving fused 4-iodoselenophene[2,3-b]thiophenes in excellent yields. In addition, the obtained chalcogenophenes were readily transformed into more complex products through palladium- or copper-catalyzed cross-coupling reactions with thiols, boronic acids, and organozinc reagents.
