1218949-63-3

Basic information

• Product Name: 1-[3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl]-2-[4-(2,4,6-trimethylbenzyl)piperazin-1-yl]-ethanone
• CAS NO: 1218949-63-3
• Molecular Weight: 451.609
• Mol File: 1218949-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl]-2-[4-(2,4,6-trimethylbenzyl)piperazin-1-yl]-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl]-2-[4-(2,4,6-trimethylbenzyl)piperazin-1-yl]-ethanone(1218949-63-3)
• EPA Substance Registry System: 1-[3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl]-2-[4-(2,4,6-trimethylbenzyl)piperazin-1-yl]-ethanone(1218949-63-3)

Safety Data

• Hazardous Substances Data: 1218949-63-3(Hazardous Substances Data)

Upstream product

• 111631-72-2 2-chloro-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one 
• 41717-26-4 1-(2,4,6-trimethylbenzyl)-piperazine 

Relevant articles and documents

N-substituted isoquinoline derivatives as potential AChE inhibitors

(Chemical Equation Presented) N-substituted donepezil-related isoquinolines have been prepared as potential acetylcholinesterase inhibitors (AChEIs). Microwave assisted procedures and solution-phase parallel synthesis were chosen to optimize the synthetic approach and improve the yields. All synthesized compounds were tested for their AChE inhibitory activity by colorimetric Ellman method and some of them (10, 13, and 28) displayed low inhibitory effects at μM concentrations.