1219359-99-5

Basic information

• Product Name: 4-hydrazino-5,6-diphenylfuro[2,3-d]pyrimidine
• Synonyms: 4-hydrazino-5,6-diphenylfuro[2,3-d]pyrimidine
• CAS NO: 1219359-99-5
• Molecular Weight: 302.335
• Mol File: 1219359-99-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-hydrazino-5,6-diphenylfuro[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydrazino-5,6-diphenylfuro[2,3-d]pyrimidine(1219359-99-5)
• EPA Substance Registry System: 4-hydrazino-5,6-diphenylfuro[2,3-d]pyrimidine(1219359-99-5)

Safety Data

• Hazardous Substances Data: 1219359-99-5(Hazardous Substances Data)

Upstream product

• 65148-07-4 4-chloro-5,6-diphenylfuro[2,3-d]pyrimidine 

Downstream Products

• 1219360-02-7 4-(4-chlorobenzylidenehydrazono)-5,6-diphenylfuro[2,3-d]pyrimidine 
• 1219360-03-8 4-(2-chlorobenzylidenehydrazono)-5,6-diphenylfuro[2,3-d]pyrimidine 
• 1219360-00-5 4-(benzylidenehydrazono)-5,6-diphenylfuro[2,3-d]pyrimidine 
• 1219360-01-6 4-(4-hydroxybenzylidenehydrazono)-5,6-diphenylfuro[2,3-d]pyrimidine 

Relevant articles and documents

Synthesis, characterization and antimicrobial evaluation of some arylidenehy drazon of uropyrimidines and thienopyrimidines

Cyclization of hetcroaromatic o-aminoestcr with formamide afforded furo[2, 3-d]pyrimidin-4(3II)-one which was then chlorinated with thionyl chloride followed by displacement by hydrazine hydrate to furnish hydrazinofuro [2, 3-d]pyrimidine. Reaction of hydrazino derivative with formic acid gave furo[3, 2-c][ 1, 2, 4]triazolo[4, 3-c]pyrimidine. Treatment of hydrazino derivative with aromatic aldehydes afforded arylidenehydrazonofuro[2, 3-d]pyrimidine derivatives. Reaction of o-aminonitrile with carbon disulphide, followed by methylation with methyl iodide and subsequent reaction with hydrazine hydrate afforded hydrazinothieno[2, 3-d]pyrimidine. 14 derivatives were synthesized. Some of these derivatives exhibited pronounced antimicrobial activities against S. typhi, S. aureus, S. dysenteriae, V. cholerae, C. lunata, A. alternata, C. corchori, F. equeseti and M. phaseolina.