121953-23-9

Basic information

• Product Name: 2-ethyl-6-phenylimidazo<2,1-b>thiazole
• Synonyms: 2-ethyl-6-phenylimidazo<2,1-b>thiazole
• CAS NO: 121953-23-9
• Molecular Weight: 228.318
• Mol File: 121953-23-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-ethyl-6-phenylimidazo<2,1-b>thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-6-phenylimidazo<2,1-b>thiazole(121953-23-9)
• EPA Substance Registry System: 2-ethyl-6-phenylimidazo<2,1-b>thiazole(121953-23-9)

Safety Data

• Hazardous Substances Data: 121953-23-9(Hazardous Substances Data)

Upstream product

• 121953-10-4 5-ethyl-2-imino-3-phenacyl-2,3-dihydrothiazole 
• 39136-60-2 5-ethylthiazol-2-amine 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 134670-54-5 C₁₃H₁₁⁽²⁾HN₂S 

Relevant articles and documents

6-thienyl and 6-phenylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase

Starting from the potent inhibitory effect of the previously described 2-methyl-6-(2-thienyl)imidazo[2,1-b]thiazole on mitochondrial complex I, we prepared a series of derivatives in order to study the effect of a different substitution at the positions 2, 5 and 6. The replacement of the thienyl group at position 6 with a phenyl group does not modify the biological behaviour of the lead compound, whereas the shift of the methyl group from position 2 to position 5 yields a compound devoid of inhibitory effects. In both the 6-thienyl and 6-phenyl series, the lengthening of the chain at position 2 has provided useful information to outline the structural determinants of the ubiquinone antagonist action in imidazothiazole derivatives.