121963-39-1

Basic information

• Product Name: 1H-Indole, 2-bromo-1-(phenylsulfonyl)-
• CAS NO: 121963-39-1
• Molecular Formula: C14H10BrNO2S
• Molecular Weight: 336.209
• Mol File: 121963-39-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 2-bromo-1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2-bromo-1-(phenylsulfonyl)-(121963-39-1)
• EPA Substance Registry System: 1H-Indole, 2-bromo-1-(phenylsulfonyl)-(121963-39-1)

Safety Data

• Hazardous Substances Data: 121963-39-1(Hazardous Substances Data)

Usage

Chemical Class

Indole derivatives

Bromo and phenylsulfonyl groups attached

2 and 1 positions on the indole ring, respectively
Potential for use in chemical reactions and synthesis of bioactive molecules
Commonly used in organic synthesis and medicinal chemistry for developing new pharmaceuticals and agrochemicals
Possible applications in material science and as a building block for complex organic molecules

Upstream product

• 139409-34-0 2-bromo-1H-indole 
• 98-09-9 benzenesulfonyl chloride 
• 40899-71-6 1-benzenesulfonylindole 

Downstream Products

• 121963-53-9 2-propyl-1-(phenylsulfonyl)indole 
• 1158373-52-4 (1-benzenesulfonyl-1H-indol-2-yl)-[3-(1-Benzenesulfonyl-1H-indol-2-yl)phenyl]methanone 
• 1158373-47-7 (1-benzenesulfonyl-1H-indol-2-yl)-[3-(1-Benzenesulfonyl-1H-indol-2-yl)phenyl]methane 
• 1158373-44-4 (1-benzenesulfonyl-1H-indol-2-yl)-[3-(1-benzenesulfonyl-1H-indol-2-yl)phenyl]methanol 
• 1158373-42-2 3-(1-benzenesulfonyl-1H-indol-2-yl)-benzaldehyde 
• 121963-45-9 1-Benzenesulfonyl-2-bromo-3-ethyl-1H-indole 
• 77507-52-9 3-ethyl-1-(phenylsulfonyl)-1H-indole 
• 121963-41-5 3-acetyl-2-bromo-1-(phenylsulfonyl)indole 

Relevant articles and documents

A convenient synthesis of 2-nitroindoles

The reaction of 2-iodo- and 2-bromoindoles with silver nitrite in aqueous acetone affords the corresponding 2-nitroindoles in modest to good yields.

Indoles, Derivatives, and Analogs Thereof and Uses Therefor

Indole derivatives and analog compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative disease or to treat a

Synthesis of Alkyl-Substituted N-Protected Indoles via Acylation and Reductive Deoxygenation

The synthesis of 2-, 3-, and 5-alkyl-1-(phenylsulfonyl)indoles involving Friedel-Crafts acylation followed by reductive deoxygenation is described.The application of this acylation-deoxygenation sequence to 3-acyl-1-(phenylsulfonyl)indoles bearing potenti