1219637-10-1Relevant articles and documents
Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae
Kudoh, Takashi,Park, Chan Sun,Lefurgy, Scott T.,Sun, Meihao,Michels, Theodore,Leyh, Thomas S.,Silverman, Richard B.
experimental part, p. 1124 - 1134 (2010/04/26)
Survival of the human pathogen Streptococcus pneumoniae requires a functional mevalonate pathway, which produces isopentenyl diphosphate, the essential building block of isoprenoids. Flux through this pathway appears to be regulated at the mevalonate kina