1219804-18-8 Usage
Description
4-Fluorobenzyl-a,a-d2 Chloride, with the CAS number 1219804-18-8, is an isotopically labeled research compound that is utilized in various scientific studies and applications. It is a derivative of benzyl chloride, featuring a fluorine atom at the para position and two deuterium atoms attached to the alpha carbon.
Uses
Used in Research and Development:
4-Fluorobenzyl-a,a-d2 Chloride is used as a research compound for the development and study of various chemical reactions and processes. Its isotopically labeled nature allows for the tracking and analysis of specific reaction pathways, providing valuable insights into the mechanisms and outcomes of these reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Fluorobenzyl-a,a-d2 Chloride is used as a synthetic intermediate for the production of various drugs and drug candidates. Its unique structure and isotopically labeled atoms can be employed to create novel compounds with potential therapeutic applications.
Used in Chemical Synthesis:
4-Fluorobenzyl-a,a-d2 Chloride is used as a reagent in chemical synthesis, particularly in the preparation of fluorinated organic compounds. The presence of the fluorine atom and deuterium atoms can influence the reactivity and selectivity of the compound, making it a valuable tool for the synthesis of complex organic molecules.
Used in Analytical Chemistry:
In analytical chemistry, 4-Fluorobenzyl-a,a-d2 Chloride can be employed as a reference material or internal standard for the quantification and identification of related compounds. Its distinct isotopic signature can help improve the accuracy and precision of analytical measurements.
Used in Material Science:
4-Fluorobenzyl-a,a-d2 Chloride may also find applications in material science, where it can be used to develop new materials with specific properties. The incorporation of fluorine and deuterium atoms into the molecular structure can lead to unique physical and chemical characteristics, potentially enhancing the performance of these materials in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1219804-18-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,8,0 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1219804-18:
(9*1)+(8*2)+(7*1)+(6*9)+(5*8)+(4*0)+(3*4)+(2*1)+(1*8)=148
148 % 10 = 8
So 1219804-18-8 is a valid CAS Registry Number.
1219804-18-8Relevant articles and documents
Side Chain Hydroxylation of Aromatic Compounds by Fungi. Part 4. Influence of the para Substituent on Kinetic Isotope Effects During Benzylic Hydroxylation by Mortierella isabellina
Holland, Herbert L.,Brown, Frances M.,Conn, Morgan
, p. 1651 - 1655 (2007/10/02)
The benzylic hydroxylation of a series of para-substituted toluenes by the fungus Mortierella isabellina has been studied by using CD3, CHD2, and CH2D methyl labelled substrates.Inter- and intramolecular primary and secondary deuterium kinetic isotope effect ratios have been determined: the intermolecular primary effects are maximal with strongly electron-withdrawing para substituents (R = CN and CF3), while the intramolecular primary effects are minimal for R = H but increase in instances where R is electron donating or withdrawing.These results are interpreted in terms of a dependence of the hydroxylation mechanism on the nature of the para substituent.
