1219813-78-1 Usage
Description
3-(2-Bromo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound that serves as an intermediate in the synthesis of various organic compounds. It is characterized by the presence of a bromoacetyl group attached to a piperidine ring, with a carboxylic acid group and a tert-butyl ester group attached to the 1-position of the piperidine. 3-(2-Bromo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester is a versatile building block in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
3-(2-Bromo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester is used as a reactant in the synthesis of oxazolobenzimidazole derivatives and analogs. These compounds are known as potentiators of metabotropic glutamate receptors, which play a crucial role in the regulation of neurotransmission in the central nervous system. The modulation of these receptors has potential therapeutic applications in the treatment of neurological disorders such as schizophrenia, anxiety, and Parkinson's disease.
Used in Organic Synthesis:
3-(2-Bromo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester is used as a versatile building block in the synthesis of various organic compounds. Its unique structure allows for the formation of a wide range of products through reactions such as nucleophilic substitution, reductive debromination, and ester hydrolysis. This makes it a valuable precursor in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1219813-78-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,8,1 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1219813-78:
(9*1)+(8*2)+(7*1)+(6*9)+(5*8)+(4*1)+(3*3)+(2*7)+(1*8)=161
161 % 10 = 1
So 1219813-78-1 is a valid CAS Registry Number.
1219813-78-1Relevant articles and documents
OXAZOLOBENZIMIDAZOLE DERIVATIVES
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Page/Page column 27, (2010/04/27)
The present invention is directed to oxazolobenzimidazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
