1220498-60-1Relevant articles and documents
Enantioselective synthesis of (+)-estrone exploiting a hydrogen bond-promoted Diels?Alder reaction
Weimar, Marko,Duerner, Gerd,Bats, Jan W.,Goebel, Michael W.
supporting information; experimental part, p. 2718 - 2721 (2010/07/17)
Starting from Danes diene and methylcyclopentenedione, (+)-estrone is synthesized along the Quinkert?Dane route in 24% total yield. The key step is an enantioselective Diels?Alder reaction promoted by an amidinium catalyst as efficiently as by a traditional Ti-TADDOLate Lewis acid.