1220710-00-8Relevant articles and documents
Design and synthesis of novel 3,4-disubstituted pyrazoles for nanomedicine applications against malignant gliomas
Comes Franchini, Mauro,Bonini, Bianca Flavia,Camaggi, Carlo Maurizio,Gentili, Denis,Pession, Annalisa,Rani, Monica,Strocchi, Elena
experimental part, p. 2024 - 2033 (2010/06/20)
A series of novel 3,4-disubstituted pyrazoles were synthesized. The cytotoxicity against U87MG glioma cell line have been investigated in vitro and three of these compounds showed promising inhibitory activity on cell growth with an IC50 lower