12211-28-8

Basic information

• Product Name: Proteinase, Bacillus subtilis, sutilain
• Synonyms: Proteinase, Bacillus subtilis, sutilain;SUTILAINS;Proteinase, Bacillus subtilis, sutilains
• CAS NO: 12211-28-8
• Molecular Weight: 0
• EINECS: 235-390-3
• Mol File: 12211-28-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Proteinase, Bacillus subtilis, sutilain(CAS DataBase Reference)
• NIST Chemistry Reference: Proteinase, Bacillus subtilis, sutilain(12211-28-8)
• EPA Substance Registry System: Proteinase, Bacillus subtilis, sutilain(12211-28-8)

Safety Data

• Hazardous Substances Data: 12211-28-8(Hazardous Substances Data)

Usage

Description

Proteinase, Bacillus subtilis, sutilain, also known as Travase, is a proteolytic enzyme derived from Bacillus subtilis cultures. It is specifically utilized for the dissolution of necrotic tissue in various medical conditions, such as secondand third-degree burns, bed sores, and ulcerated wounds. Its compatibility with certain antibiotics, such as penicillin, streptomycin, and neomycin, makes it a valuable component in wound care, although it is contraindicated with substances like detergents and anti-infectives that can denature the enzyme preparation. Mafenide acetate is also compatible with sutilains, further expanding its applications in medical treatments.

Uses

Used in Wound Care Industry:
Proteinase, Bacillus subtilis, sutilain is used as a topical enzyme for the dissolution of necrotic tissue in secondand third-degree burns, bed sores, and ulcerated wounds. Its application aids in the healing process by clearing away dead or damaged tissue, promoting a cleaner wound environment, and preparing the area for effective treatment and recovery.
Used in Pharmaceutical Formulations:
Proteinase, Bacillus subtilis, sutilain is used as an active ingredient in pharmaceutical formulations under the brand name Travase (Abbott). This enzyme-based product is specifically designed to target and dissolve necrotic tissue, supporting the body's natural healing mechanisms and providing a more conducive environment for wound recovery.
Used in Compatibility Studies:
In the development of new wound care treatments, Proteinase, Bacillus subtilis, sutilain is used as a reference enzyme to study compatibility with other substances, such as antibiotics and other wound care agents. This ensures that the enzyme's effectiveness is not compromised when used in combination with other treatments, thereby maximizing the overall therapeutic outcome for patients.