1221682-74-1

Basic information

• Product Name: (E)-4-(2-butoxycarbonylvinyl)benzoic acid ethyl ester
• Synonyms: (E)-4-(2-butoxycarbonylvinyl)benzoic acid ethyl ester
• CAS NO: 1221682-74-1
• Molecular Weight: 276.332
• Mol File: 1221682-74-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (E)-4-(2-butoxycarbonylvinyl)benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(2-butoxycarbonylvinyl)benzoic acid ethyl ester(1221682-74-1)
• EPA Substance Registry System: (E)-4-(2-butoxycarbonylvinyl)benzoic acid ethyl ester(1221682-74-1)

Safety Data

• Hazardous Substances Data: 1221682-74-1(Hazardous Substances Data)

Upstream product

• 19819-94-4 4-allyl-benzoic acid ethyl ester 
• 71-36-3 butan-1-ol 
• 141-32-2 acrylic acid n-butyl ester 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 51934-41-9 4-iodobenzoic acid ethyl ester 

Relevant articles and documents

N,N′-Mono substituted acyclic thioureas: Efficient ligands for the palladium catalyzed Heck reaction of deactivated aryl bromides

A series of N,N′-mono substituted acyclic thiourea ligands are found to be highly active phosphine-free catalysts for palladium catalyzed Heck reaction of aryl iodides and bromides with olefins. We have achieved high turnover numbers for aryl iodides with olefins (TONs up to 970,000 for the reaction of iodobenzene with styrene).

A practical method for heterogeneously-catalyzed Mizoroki–Heck reaction: Flow system with adjustment of microwave resonance as an energy source

The microwave-assisted and continuous-flow Mizoroki–Heck reaction using a heterogeneous palladium catalyst supported on the anion-exchange resin DIAION WA30 (7% Pd/WA30) is described. The microwave resonance is finely adjusted to 2.4 GHz according to the electric permittivity of the reaction medium for efficient heating. Organic solvents, such as acetonitrile, N,N-dimethylacetamide, and toluene, can be sufficiently heated even with a low intensity of microwave irradiation in a 7% Pd/WA30-packed, glass tube-shaped catalyst cartridge, which was designed based on the electric permittivity of the solvents. The catalyst cartridge can be continuously reused at least 5 runs without exchange.

Novel isoxazoline ligand with ferrocene backbone: Preparation and application in Heck reaction with water as solvent

Two novel isoxazoline N,N-bidentate ligands with ferrocene backbone have been synthesized and employed for the palladium-catalyzed Heck coupling reaction. Among them, 1,3-bis-(5-ferrocenylisoxazoline-3-yl)benzene was found to be thermally stable and a highly effective ligand for Heck coupling reaction in neat water without N2 protection, affording the desired coupling products in good to excellent yield with high diastereoselectivity. The developed catalytic system was also well workable for 1,2-disubstituted alkenes, which were less involved in the Heck reaction for its larger steric hindrance. Copyright