1221885-59-1

Basic information

• Product Name: deutetrabenazine
• CAS NO: 1221885-59-1
• Molecular Weight: 323.381
• Mol File: 1221885-59-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: deutetrabenazine(CAS DataBase Reference)
• NIST Chemistry Reference: deutetrabenazine(1221885-59-1)
• EPA Substance Registry System: deutetrabenazine(1221885-59-1)

Safety Data

• Hazardous Substances Data: 1221885-59-1(Hazardous Substances Data)

Upstream product

• 1069-62-1 trimethyl[2-(2-methylpropyl)-3-oxobutyl]azanium iodide 
• 1849-29-2 1,1,1-trideuteromethanol 
• 89929-27-1 2-Oxo-3-isobutyl-9,10-dihydroxy-1,2,3,4,6,7-hexahydro-11bH-benzochinolizin 
• 86497-40-7 trimethyl-(5-methylhex-2-en-2-yloxy)silane 
• 1351951-84-2 d₆-N-[2-(3,4-dimethoxy-phenyl)ethyl]formamide 
• 1351951-81-9 tert-butyl N-[2-[3,4-bis(2H₆)methoxyphenyl]ethyl]carbamate 
• 1162658-07-2 d₆-2-(3,4-dimethoxyphenyl)ethanamine 
• 91342-74-4 3-[(dimethylamino)methyl]-5-methylhexan-2-one 
• 1221885-61-5 d₆-6,7-dimethoxy-3,4-dihydroisoquinoline 
• 37034-31-4 N-(tert-butoxycarbonyl)dopamine 
• 62-31-7 dopamine hydrochloride 
• 110-12-3 5-Methyl-2-hexanone 

Relevant articles and documents

METHODS AND INTERMEDIATES FOR PREPARING DEUTETRABENAZINE

Disclosed is a process for the preparation of deutetrabenazine and intermediates useful in the preparation thereof. Disclosed are also process for making amorphous deutetrabenazine.

BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2

The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.

NOVEL PROCESS FOR PREPARATION OF TETRABENAZINE AND DEUTETRABENAZINE

The present invention provides process for preparation of dihydroxy benzoquinoline compound (III) comprising reacting dihydroxy isoquinoline compound (IV) or a salt thereof with (2-acetyl-4-methyl-pentyl)-trimethyl-ammonium iodide (V) and further 5 converting it to tetrabenazine (I) and deutetrabenazine (II).