1222094-31-6Relevant articles and documents
Application of laccase/DDQ as a new bioinspired catalyst system for the aerobic oxidation of tetrahydroquinazolines and Hantzsch 1,4-dihydropyridines
Shariati, Mastaneh,Imanzadeh, Gholamhassan,Rostami, Amin,Ghoreishy, Nadya,Kheirjou, Somayyeh
, p. 337 - 346 (2019/04/25)
Laccase/DDQ as a new bioinspired quinone-based cooperative catalytic system was used for the biomimetic aerobic oxidative synthesis of 2-substituted quinazolines and Hantzsch pyridines from the oxidative cyclocondensation of 2-aminobenzylamine and aldehyd
KOtBu-mediated stereoselective addition of quinazolines to alkynes under mild conditions
Zhao, Dan,Shen, Qi,Zhou, Yu-Ren,Li, Jian-Xin
supporting information, p. 5908 - 5912 (2013/09/12)
A facile alkenylation of quinazolines with unactivated terminal alkynes has been achieved in the presence of KOtBu without the aid of any transition metal catalysts. The reaction is carried out under very mild conditions and shows a high stereoselectivity
Highly efficient one-pot synthesis of 2-substituted quinazolines and 4H-benzo[d][1,3]oxazines via cross dehydrogenative coupling using sodium hypochlorite
Maheswari, C. Uma,Kumar, G. Sathish,Venkateshwar,Kumar, R. Arun,Kantam, M. Lakshmi,Reddy, K. Rajender
supporting information; experimental part, p. 341 - 346 (2010/04/28)
This communication describes a catalyst-free synthesis of 2-substituted quinazolines and 4H-benzo[d][1,3]oxazines using commericially available sodium hypochlorite as oxidant. Operational simplicity, mild reaction conditions and the ability to construct structurally diverse 2-quinazolines and 2-substituted 4H-benzo[d][1,3]oxazines by this method render it to be a practical alternative for the synthesis of these heterocycles.
