1222102-51-3 Usage
Description
(R)-4-[(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(t-butoxymethyl)piperazin-2-one(tartrate), also known as Evogliptin Tartrate, is a chiral compound with a complex molecular structure. It features a piperazin-2-one core, a t-butoxymethyl group, and a trifluorophenylbutanoyl moiety. The presence of stereocenters in the molecule results in distinct R-configurations, which are crucial for its biological activity and selectivity.
Uses
Used in Pharmaceutical Industry:
Evogliptin Tartrate is used as an intermediate in the synthesis of dipeptidyl peptidase-IV (DPP-IV) inhibitors and their derivatives. These inhibitors play a vital role in the treatment of type 2 diabetes by modulating the incretin system, which helps regulate blood glucose levels. The R-configurations in Evogliptin Tartrate contribute to the selectivity and potency of the resulting DPP-IV inhibitors, making it a valuable component in the development of effective anti-diabetic medications.
Check Digit Verification of cas no
The CAS Registry Mumber 1222102-51-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,2,1,0 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1222102-51:
(9*1)+(8*2)+(7*2)+(6*2)+(5*1)+(4*0)+(3*2)+(2*5)+(1*1)=73
73 % 10 = 3
So 1222102-51-3 is a valid CAS Registry Number.
1222102-51-3Relevant articles and documents
PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETES OR OBESITY COMPRISING A COMPOUND THAT INHIBITS ACTIVITY OF DIPEPTIDYL PEPTIDASE-IV, AND OTHER ANTIDIABETIC OR ANTIOBESITY AGENTS AS ACTIVE INGREDIENTS
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, (2017/12/15)
The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV(DPP-IV), a pharmaceutically acceptable
METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE
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Page/Page column 10, (2012/02/01)
The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.