1223053-77-7

Basic information

• Product Name: (1R,2R,4S,5S)-2,4-diazido-5-(methoxymethoxy)cyclo-hexyl acetate
• Synonyms: (1R,2R,4S,5S)-2,4-diazido-5-(methoxymethoxy)cyclo-hexyl acetate
• CAS NO: 1223053-77-7
• Molecular Weight: 284.275
• Mol File: 1223053-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,4S,5S)-2,4-diazido-5-(methoxymethoxy)cyclo-hexyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,4S,5S)-2,4-diazido-5-(methoxymethoxy)cyclo-hexyl acetate(1223053-77-7)
• EPA Substance Registry System: (1R,2R,4S,5S)-2,4-diazido-5-(methoxymethoxy)cyclo-hexyl acetate(1223053-77-7)

Safety Data

• Hazardous Substances Data: 1223053-77-7(Hazardous Substances Data)

Upstream product

• 150587-19-2 methoxymethoxy chloride 
• 894423-96-2 (1R,2R,4S,5S)-2,4-diazido-5-hydroxycyclohexyl acetate 

Relevant articles and documents

Synthesis of 2,4,5-triaminocyclohexanecarboxylic acid as a novel 2-deoxystreptamine mimic

Since aminoglycosides have been known to exert their antibacterial activities by binding to various RNA targets, 2-deoxystreptamine served as a particularly important model in understanding RNA-small molecule interaction. Herein, 2,4,5-triaminocyclohexanecarboxylic acid was prepared as a novel 2-deoxystreptamine (2-DOS) mimic, which replaces highly flexible glycosidic bonds of aminoglycosides with amide bonds and may improve binding selectivity toward RNA targets through increased rigidity and additional hydrogen-bonding capability. This unnatural g-amino acid can also be used as a potential component for synthetic foldamers.