122348-66-7

Basic information

• Product Name: (R)-(+)-N-(2',2'-dimethylpropyl)-1-phenylethylamine
• Synonyms: (R)-(+)-N-(2',2'-dimethylpropyl)-1-phenylethylamine
• CAS NO: 122348-66-7
• Molecular Weight: 191.316
• Mol File: 122348-66-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-(+)-N-(2',2'-dimethylpropyl)-1-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-N-(2',2'-dimethylpropyl)-1-phenylethylamine(122348-66-7)
• EPA Substance Registry System: (R)-(+)-N-(2',2'-dimethylpropyl)-1-phenylethylamine(122348-66-7)

Safety Data

• Hazardous Substances Data: 122348-66-7(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 630-19-3 pivalaldehyde 
• 594-19-4 tert.-butyl lithium 
• 122348-64-5 (R)-N-(triphenyl-2,2,2-ethyl)phenyl-1 ethylamine 
• 15501-33-4 neopentyl iodide 
• 91797-84-1 (R)-(+)-N-(1-phenylethyl)-2,2-dimethylpropanamide 

Downstream Products

• 116468-82-7 lithium- 

Relevant articles and documents

Use of N,N'-dimethylpropyleneurea (DMPU) as solvent in the efficient preparation of enantiomerically pure secondary amines

The monoalkylation of (R)- and (S)-1-phenylethylamine proceeds readily with DMPU as the solvent. An efficient procedure was then developed for the high-yield preparation of the chiral secondary amines N-benzyl-, N-isopropyl-, N-(2-biphenylyl)methyl-, N-(diphenyl)methyl-, and N-(2,2-dimethyl)propyl-1-phenylethylamine, in enantiomerically pure form.

Amidures de lithium chiraux; β-elimination de trityllithium a partir d'un amidure de lithium

The synthesis of a chiral secondary amine bearing a N-CH2-trityl moiety is described.The formation of the corresponding lithium amide results in the β-elimination of trityllithium, leading to an intermediate methyleneamiine, which can react with nucleophiles.