122457-36-7

Basic information

• Product Name: (Z)-3-Bromo-4-methoxy-4-oxo-2-butenoic acid
• Synonyms: (Z)-3-Bromo-4-methoxy-4-oxo-2-butenoic acid
• CAS NO: 122457-36-7
• Molecular Formula: C₅H₅BrO₄
• Molecular Weight: 208.99
• Mol File: 122457-36-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (Z)-3-Bromo-4-methoxy-4-oxo-2-butenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-Bromo-4-methoxy-4-oxo-2-butenoic acid(122457-36-7)
• EPA Substance Registry System: (Z)-3-Bromo-4-methoxy-4-oxo-2-butenoic acid(122457-36-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 122457-36-7(Hazardous Substances Data)

Upstream product

• 5926-51-2 bromomaleic anhydride 
• 67-56-1 methanol 
• 3052-50-4 monomethyl maleate 

Downstream Products

• 122457-78-7 (E)-methyl 2-bromo-3-(3-vinylcyclohex-2-enyloxycarbonyl)acrylate 
• 115477-31-1 (1RS,2SR,6RS)-methyl 8-benzyl-2-bromo-9-oxo-8-azabicyclo<4.3.0>non-4-ene-2-carboxylate 

Relevant articles and documents

Preparation method of chlorantraniliprole

The invention relates to the technical field of synthesis processes of insecticides, and discloses a preparation method of chlorantraniliprole, which comprises the following steps: 1) adding 4-8 partsof maleic anhydride and 4-8 parts of methanol into a single-necked bottle, stirring the mixture, heating to 50 DEG C, and carrying out heat preservation reaction for 0.5-1.5 hours to obtain monomethyl maleate; and 2) cooling 80-120 parts of a hydrogen bromide-glacial acetic acid solution to 0 DEG C, then dropwise adding 3-5 parts of the monomethyl maleate, after addition is completed, carrying out heat preservation and stirring for 3-7 min, so that a large amount of a yellow viscous substance appears, and the monomethyl 3-bromomaleate can be prepared. The invention discloses a preparation method of chlorantraniliprole. The maleic anhydride, 2,3-dichloropyridine and 2-amino-3-methylbenzoic acid are adopted as starting materials to synthesize the target compound chlorantraniliprole througha convergent reaction. The structure is determined through HNMR, the route is mild in reaction condition, easy and convenient to operate and separate, raw materials are easy to obtain, special equipment is not needed, industrial production is easy to achieve, the action mechanism is novel and unique, and wide application and development prospects are achieved.