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1224724-39-3

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1224724-39-3 Usage

General Description

1H-Indole-7-carboxylic acid, 4-bromo-, methyl ester is a chemical compound with the formula C11H9BrNO2. It is a methyl ester derivative of 1H-Indole-7-carboxylic acid, which is a naturally occurring compound found in various plants and animals. The 4-bromo substitution on the indole ring makes this compound potentially useful in medicinal chemistry for the development of new drugs. It may have biological activities and therapeutic properties that could be explored for potential pharmaceutical applications. 1H-Indole-7-carboxylic acid, 4-bromo-, methyl ester can be synthesized through chemical reactions and is commonly used as a reagent in organic synthesis and pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 1224724-39-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,7,2 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1224724-39:
(9*1)+(8*2)+(7*2)+(6*4)+(5*7)+(4*2)+(3*4)+(2*3)+(1*9)=133
133 % 10 = 3
So 1224724-39-3 is a valid CAS Registry Number.

1224724-39-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 4-bromo-1H-indole-7-carboxylate

1.2 Other means of identification

Product number -
Other names methyl 4-bromo-1H-indole-7-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1224724-39-3 SDS

1224724-39-3Relevant articles and documents

Compound serving as protein kinase inhibitor and application of compound

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Paragraph 0233-0234; 0239-0240, (2021/04/07)

The invention discloses a compound used as a protein kinase inhibitor and application of the compound, the compound has an obvious inhibition effect on protein kinase activity, can be used as a BTK inhibitor for preparing medicines for treating BTK-mediated diseases such as malignant tumors, autoimmune diseases and the like, and has wide application prospect.

SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE

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Page/Page column 300, (2017/08/01)

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell proliferative disorders, such as cancer, wherein A, R2, R3, R10, E1, E2, E3, Y, and Z are as defined herein.

PRIMARY CARBOXAMIDES AS BTK INHIBITORS

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Page/Page column 95, (2015/01/16)

The invention provides carboxamide compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions, including rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis, Crohn's disease, inflammatory bowel disease, ulcerative colitis, psoriatic arthritis, psoriasis, ankylosing spondylitis, interstitial cystitis, asthma, systemic lupus erythematosus, lupus nephritis, B cell chronic lymphocytic lymphoma, multiple sclerosis, chronic lymphocytic leukemia, small lymphocytic lymphoma, mantle cell lymphoma, B-cell non-Hodgkin's lymphoma, activated B-celllike diffuse large B-cell, lymphoma, multiple myeloma, diffuse large B-celllymphoma, follicular lymphoma, hairy cell leukemia or Lymphoblastic lymphoma.

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