122481-11-2Relevant articles and documents
NOVEL TETRAHYDROISOQUINOLINES AND TERAHYDRONAPHTHYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
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Page/Page column 19, (2018/05/24)
The present invention provides novel compounds having the general formula (I): wherein R1, R 2, R 3, U, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
Cyclic gyrase and topoisomerase IV inhibitor
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Paragraph 0208; 0209; 0210, (2017/01/02)
The invention belongs to the technical field of medicament, and particularly relates to a compound shown in formula (I) (please see the formula (I) in the description), and acceptable salt, ester or stereoisomer of the compound in pharmacy. R1, R2, a ring
Nitropyrazoles 4. N-Amination under control of the pH of the medium
Vinogradov, V. M.,Dalinger, I. L.,Gulevskaya, V. I.,Shevelev, S. A.
, p. 1369 - 1371 (2007/10/02)
A preparative method of N-amination of pyrazoles bearing nitro groups and other electron withdrawing substituents in the pyrazole ring with hydroxylamine-O-sulfonic acid involving control of the pH of the medium has been elaborated.A series of previously unknown pyrazoles has been prepared.Basicities (pKBH+) of 1-aminopyrazole and 1-amino-4-nitropyrazole have been measured and differences between the basicities of the C- and N-amino groups for the pyrazole series have been revealed. - Key words: nitropyrazoles, N-aminopyrazoles, N-amination.
