1224934-58-0Relevant articles and documents
Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies
Nakahara, Toru,Nomura, Wataru,Ohba, Kenji,Ohya, Aki,Tanaka, Tomohiro,Hashimoto, Chie,Narumi, Tetsuo,Murakami, Tsutomu,Yamamoto, Naoki,Tamamura, Hirokazu
, p. 709 - 714 (2010)
A synthetic antigen targeting membrane-fusion mechanism of HIV-1 has a newly designed template with C3-symmetric linkers mimicking N36 trimeric form. The antiserum produced by immunization of the N36 trimeric form antigen showed structural preference in b