1225327-16-1 Usage
Description
5-(2-(phenylsulfonyl)ethyl)-1H-indole is an organic compound with the chemical formula C16H15NO2S. It is a derivative of indole, a heterocyclic aromatic organic compound, and features a phenylsulfonylethyl group attached to the 5-position of the indole ring. 5-(2-(phenylsulfonyl)ethyl)-1H-indole is characterized by its unique chemical structure and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
5-(2-(phenylsulfonyl)ethyl)-1H-indole is used as an intermediate in the synthesis of pharmaceutical compounds for the treatment of various diseases. Its unique chemical structure allows it to be a versatile building block in the development of new drugs with potential therapeutic benefits.
Used in Chemical Research:
5-(2-(phenylsulfonyl)ethyl)-1H-indole is used as a research compound in the field of organic chemistry. It serves as a valuable tool for studying the properties and reactions of indole derivatives, as well as for exploring new synthetic routes and methodologies.
Used in Material Science:
5-(2-(phenylsulfonyl)ethyl)-1H-indole can be used in the development of new materials with specific properties, such as organic semiconductors, sensors, or other functional materials. Its unique structure and potential for modification make it an interesting candidate for these applications.
Used in Analytical Chemistry:
5-(2-(phenylsulfonyl)ethyl)-1H-indole can be employed as a reference compound or standard in analytical chemistry for the calibration of instruments, the development of new analytical methods, or the study of chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1225327-16-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,5,3,2 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1225327-16:
(9*1)+(8*2)+(7*2)+(6*5)+(5*3)+(4*2)+(3*7)+(2*1)+(1*6)=121
121 % 10 = 1
So 1225327-16-1 is a valid CAS Registry Number.
1225327-16-1Relevant articles and documents
Magnesium catalyzed dephenylsulfonylation: Synthesis of 5-ethyl-1H-indole
Rao, S. Venkat,Shrikant, H. Havale,Kumar, B. Sanjith,Krishna, G. Siva
, p. 2232 - 2234 (2017)
A novel magnesium metal catalyzed synthesis of 5-ethyl-1H-indole from 5-[2-(phenyl sulfonyl)ethyl]-1H-indole by dephenylsulfonylation mechanism providing an alternative and attractive approach to 5-ethyl-1H-indole with high yields. This approach is for both the protected and unprotected indoles.
One-pot three-component sulfone synthesis exploiting palladium-catalysed aryl halide aminosulfonylation
Richards-Taylor, Charlotte S.,Blakemore, David C.,Willis, Michael C.
, p. 222 - 228 (2014/01/06)
A palladium-catalysed aminosulfonylation process is used as the key-step in a one-pot, three-component sulfone synthesis. The process combines aryl-, heteroaryl- and alkenyl iodides with a sulfonyl unit and an electrophilic coupling fragment. The sulfonyl unit is delivered in the form of an aminosulfonamide, which then serves as a masked sulfinate. The sulfinate is combined, in situ, with an electrophilic coupling partner, such as a benzylic, allylic or alkyl halide, an electron-poor arene, or a cyclic epoxide, to provide the corresponding sulfone products in good to excellent yields. The mild reaction conditions and use of commercially available reaction components allows the easy preparation of a broad range of sulfones featuring a variety of functional groups. The process obviates the need to employ thiol starting materials, and oxidative operations.
A NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN
-
, (2013/07/25)
The present invention relates to a novel process for the preparation of (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole and its intermediates thereof.
