1225380-87-9

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-(2,2-difluoroethyl)-, 1,1-diMethylethyl ester
• Synonyms: 1-Piperazinecarboxylic acid, 4-(2,2-difluoroethyl)-, 1,1-diMethylethyl ester;4-(2,2-Difluoro-ethyl)-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 1225380-87-9
• Molecular Formula: C11H20F2N2O2
• Molecular Weight: 250.2855064
• Mol File: 1225380-87-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-(2,2-difluoroethyl)-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-(2,2-difluoroethyl)-, 1,1-diMethylethyl ester(1225380-87-9)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-(2,2-difluoroethyl)-, 1,1-diMethylethyl ester(1225380-87-9)

Safety Data

• Hazardous Substances Data: 1225380-87-9(Hazardous Substances Data)

Usage

Family

piperazinecarboxylic acid ester

Common uses

precursor in the synthesis of pharmaceutical compounds and organic molecules

Potential applications

development of new drugs, building block for medicinal chemistry research

Fields of use

pharmaceuticals and chemical synthesis

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Relevant articles and documents

An Improved Stereocontrolled Access Route to Piperidine or Azepane β-Amino Esters and Azabicyclic β- and γ-Lactams; Synthesis of Novel Functionalized Azaheterocyles

An improved, efficient synthesis of some functionalized saturated azaheterocycles has been accomplished by controlled functionalization of various readily available cyclic compounds containing ring C=C bond. The stereocontrolled synthetic concept was based on the oxidative ring cleavage of various unsaturated scaffolds across ozonolysis followed by ring closing with double reductive amination with primary alkylamines or fluorinated alkylamines. The protocol provided versatile azaheterocyclic derivatives with a piperidine or azepane framework.

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