1226790-29-9

Basic information

• Product Name: (3S)-6-bromo-2,3-dihydro-7-methyl-5-nitro-3-[Boc-L-4-methylphenylalanyl]-1H-pyrrolo[1,2-a]benzimidazole
• Synonyms: (3S)-6-bromo-2,3-dihydro-7-methyl-5-nitro-3-[Boc-L-4-methylphenylalanyl]-1H-pyrrolo[1,2-a]benzimidazole
• CAS NO: 1226790-29-9
• Molecular Weight: 572.459
• Mol File: 1226790-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S)-6-bromo-2,3-dihydro-7-methyl-5-nitro-3-[Boc-L-4-methylphenylalanyl]-1H-pyrrolo[1,2-a]benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-6-bromo-2,3-dihydro-7-methyl-5-nitro-3-[Boc-L-4-methylphenylalanyl]-1H-pyrrolo[1,2-a]benzimidazole(1226790-29-9)
• EPA Substance Registry System: (3S)-6-bromo-2,3-dihydro-7-methyl-5-nitro-3-[Boc-L-4-methylphenylalanyl]-1H-pyrrolo[1,2-a]benzimidazole(1226790-29-9)

Safety Data

• Hazardous Substances Data: 1226790-29-9(Hazardous Substances Data)

Upstream product

• 80102-27-8 (2S)-3-(4-methylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid 
• 244152-11-2 (S)-(+)-3-amino-6-bromo-2,3-dihydro-7-methyl-5-nitro-1H-pyrrolo[1,2-a]benzimidazole 

Relevant articles and documents

Triple molecular target approach to selective melanoma cytotoxicity

Phenylalanine-linked pyrrolo[1,2-a]benzimidazoles were successfully designed to target melanoma cells in vitro. Our design utilised three molecular targets: a phenylalanine pump, the reducing enzyme DT-diaphorase, and IMP dehydrogenase. We describe the synthesis of these compounds as well as the results of in vitro, in vivo, and QSAR studies.