1226876-75-0

Basic information

• Product Name: ethyl (2E,6E)-7-{4-{[(tert-butyl)diphenyl-silyl]oxy}phenyl}-5-ethenyl-5-methylhepta-2,6-dienoate
• Synonyms: ethyl (2E,6E)-7-{4-{[(tert-butyl)diphenyl-silyl]oxy}phenyl}-5-ethenyl-5-methylhepta-2,6-dienoate
• CAS NO: 1226876-75-0
• Molecular Weight: 524.775
• Mol File: 1226876-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2E,6E)-7-{4-{[(tert-butyl)diphenyl-silyl]oxy}phenyl}-5-ethenyl-5-methylhepta-2,6-dienoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2E,6E)-7-{4-{[(tert-butyl)diphenyl-silyl]oxy}phenyl}-5-ethenyl-5-methylhepta-2,6-dienoate(1226876-75-0)
• EPA Substance Registry System: ethyl (2E,6E)-7-{4-{[(tert-butyl)diphenyl-silyl]oxy}phenyl}-5-ethenyl-5-methylhepta-2,6-dienoate(1226876-75-0)

Safety Data

• Hazardous Substances Data: 1226876-75-0(Hazardous Substances Data)

Upstream product

• 1226876-74-9 ethyl (2E,6E)-5-ethenyl-7-iodo-5-methylhepta-2,6-dienoate 
• 127481-94-1 1-bromo-4-[[(1,1-dimethylethyl)-diphenylsilyl]-oxy]-benzene 

Downstream Products

• 1226876-76-1 (3E,7E)-8-{4-{[(tert-butyl)diphenylsilyl]oxy}phenyl}-6-ethenyl-2,6-dimethylocta-3,7-dien-2-ol 

Relevant articles and documents

Synthesis of racemic Δ3-2-hydroxybakuchiol and its analogues

The first synthetic approach to (±)-Δ3-2- hydroxybakuchiol (=4-[(1E,5E)-3-ethenyl-7-hydroxy-3,7-dimethylocta-1,5-dien-1- yl]phenol; 14) and its analogues 13a - 13f was developed by 12 steps (Schemes 2 and 3). The key features of the approach are the construction of the quaternary C-center bearing the ethenyl group by a Johnson - Claisen rearrangement (→6); and of an (E)-alkenyl iodide via a Takai - Utimoto reaction (→11); and an arylation via a Negishi cross-coupling reaction (→12e - 12f).