1226894-86-5

Basic information

• Product Name: N-{[1-(2-(4-(4-fluorobenzoyl)piperazine-1-yl)ethyl)-pyrrolidine-(3R)-yl-carbamoyl]-methyl}-3-trifluoromethylbenzamide
• CAS NO: 1226894-86-5
• Molecular Weight: 549.568
• Mol File: 1226894-86-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-{[1-(2-(4-(4-fluorobenzoyl)piperazine-1-yl)ethyl)-pyrrolidine-(3R)-yl-carbamoyl]-methyl}-3-trifluoromethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{[1-(2-(4-(4-fluorobenzoyl)piperazine-1-yl)ethyl)-pyrrolidine-(3R)-yl-carbamoyl]-methyl}-3-trifluoromethylbenzamide(1226894-86-5)
• EPA Substance Registry System: N-{[1-(2-(4-(4-fluorobenzoyl)piperazine-1-yl)ethyl)-pyrrolidine-(3R)-yl-carbamoyl]-methyl}-3-trifluoromethylbenzamide(1226894-86-5)

Safety Data

• Hazardous Substances Data: 1226894-86-5(Hazardous Substances Data)

Upstream product

• 1261061-88-4 C₁₇H₂₂F₃N₃O₅S 
• 102391-98-0 1-(4-fluorobenzoyl)piperazine 

Relevant articles and documents

PIPERAZINYL 3-AMINOPYRROLIDINE DERIVATIVES AS A CCR2 ANTAGONIST

The present invention relates to compounds of chemical formula I and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteri

Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists

Novel 3-aminopyrrolidine derivatives were synthesized and evaluated for their antagonistic activity against human chemokine receptor 2. Structure-activity studies on 3-aminopyrrolidine incorporating heteroatomic carbocycle moieties led to piperidine compo