122690-15-7Relevant articles and documents
A SIMPLE PREPARATION OF S-ALKYL HOMOCYSTEINE DERIVATIVES: S-PHOSPHONOMETHYL HOMOCYSTEINES AS INHIBITORS OF GLUTAMINE SYNTHETASE
Logusch, Eugene W.
, p. 6055 - 6058 (1988)
A facile synthesis of S-alkyl homocysteines is described which features the coupling of sodium alkyl thiolates with methyl 4-bromo-2-phthalimidobutyrate, followed by hydrolysis.This approach is exemplified by the synthesis of S-phosphonomethyl homocysteine sulfone, a new inhibitor of the enzyme glutamine synthetase.
