1227258-66-3

Basic information

• Product Name: C₂₂H₂₁N₅O₂S
• Synonyms: C₂₂H₂₁N₅O₂S
• CAS NO: 1227258-66-3
• Molecular Weight: 419.507
• Mol File: 1227258-66-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₁N₅O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₁N₅O₂S(1227258-66-3)
• EPA Substance Registry System: C₂₂H₂₁N₅O₂S(1227258-66-3)

Safety Data

• Hazardous Substances Data: 1227258-66-3(Hazardous Substances Data)

Upstream product

• 57597-64-5 7-diethylaminocoumarine-3-aldehyde 
• 22706-11-2 3-phenyl-4-amino-5-mercapto-1,2,4-triazole 
• 17754-90-4 4-(Diethylamino)salicylaldehyde 

Relevant articles and documents

Rationally designed fluorescence 'turn-on' sensor for Cu2+

A rationally designed, coumarin-based fluorescent sensor imino-coumarin (IC) displays high selectivity for Cu2+ over a variety of competing metal ions in aqueous solution with a significant fluorescence increase. DFT/TDDFT calculations support that the fluorescence 'turn-on' of IC originates from blocking the electron transfer of the nitrogen lone pair upon complexation with Cu2+. IC was successfully applied to microscopic imaging for detection of Cu2+ in LLC-MK2 cells (in vitro) and several living organs (in vivo).