1227380-62-2

Basic information

• Product Name: (R)-(+)-2,4-dihydroxy-3,3-dimethyl-N-(4-methyl-sulfanyl-benzyl)butyramide
• CAS NO: 1227380-62-2
• Molecular Weight: 283.392
• Mol File: 1227380-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(+)-2,4-dihydroxy-3,3-dimethyl-N-(4-methyl-sulfanyl-benzyl)butyramide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2,4-dihydroxy-3,3-dimethyl-N-(4-methyl-sulfanyl-benzyl)butyramide(1227380-62-2)
• EPA Substance Registry System: (R)-(+)-2,4-dihydroxy-3,3-dimethyl-N-(4-methyl-sulfanyl-benzyl)butyramide(1227380-62-2)

Safety Data

• Hazardous Substances Data: 1227380-62-2(Hazardous Substances Data)

Upstream product

• 83171-39-5 4-(methylthio)benzylamine 
• 599-04-2 (R)-Pantolacton 

Downstream Products

• 1227380-64-4 (R)-(+)-3-hydroxy-4,4-dimethyl-1-(4-methyl-sulfanyl-benzyl)pyrrolidin-2-one 

Relevant articles and documents

Rational design of a topical androgen receptor antagonist for the suppression of sebum production with properties suitable for follicular delivery

A novel nonsteroidal androgen receptor antagonist, (R)-4-(1-benzyl-4,4- dimethyl-2-oxopyrrolidin-3-yloxy)-2-(trifluoromethyl)benzonitrile (1), for the topical control of sebum production is reported. This compound, which is potent, selective, and efficacious in the clinically validated golden Syrian hamster ear animal model, was designed to be delivered to the pilosebaceous unit, the site of action, preferentially by the follicular route.