1227403-16-8

Basic information

• Product Name: 1-allyl-2-(phenyl)-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-allyl-2-(phenyl)-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 1227403-16-8
• Molecular Weight: 249.356
• Mol File: 1227403-16-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-allyl-2-(phenyl)-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-allyl-2-(phenyl)-1,2,3,4-tetrahydroisoquinoline(1227403-16-8)
• EPA Substance Registry System: 1-allyl-2-(phenyl)-1,2,3,4-tetrahydroisoquinoline(1227403-16-8)

Safety Data

• Hazardous Substances Data: 1227403-16-8(Hazardous Substances Data)

Upstream product

• 3340-78-1 2-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 3066-75-9 allyl diethyl phosphate 
• 41852-27-1 2-phenyl-3,4-dihydroisoquinolin-2-ium bromide 
• 1730-25-2 allylmagnesium bromide 
• 556-56-9 allyl iodid 
• 106-95-6 allyl bromide 
• 108-86-1 bromobenzene 
• 73086-81-4 1-allyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 4873-09-0 allyl tosylate 
• 591-50-4 iodobenzene 
• 18925-10-5 allylzinc bromide 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Relevant articles and documents

Redox-neutral α-allylation of amines by combining palladium catalysis and visible-light photoredox catalysis

An unprecedented α-allylation of amines was achieved by combining palladium catalysis and visible-light photoredox catalysis. In this dual catalysis process, the catalytic generation of allyl radical from the corresponding π-allylpalladium intermediate wa

Tunable Redox Potential Photocatalyst: Aggregates of 2,3-Dicyanopyrazino Phenanthrene Derivatives for the Visible-Light-Induced α-Allylation of Amines

This work highlights the tunable redox potential of 6,11-dibromo-2,3-dicyanopyrazinophenanthrene (DCPP3) aggregates, which can be formed through physical π-πstacking interactions with other DCPP3 monomers. Electrochemical and scanning electron microscopy showed that the reduction potential of [DCPP3]n aggregates could be increased by decreasing their size. The size of [DCPP3]n aggregates could be regulated by controlling the concentration of DCPP3 in an organic solvent. As such, a fundamental understanding of this tunable redox potential is essential for developing new materials for photocatalytic applications. The [DCPP3]n aggregates as a visible-light photocatalyst in combination with Pd catalysts in the visible-light-induced α-allylation of amines were used. This [DCPP3]n photocatalyst exhibits excellent photo- and electrochemical properties, including a remarkable visible-light absorption, long excited-state lifetime (16.6 μs), good triplet quantum yield (0.538), and high reduction potential (Ered([DCPP3]n/[DCPP3]n-) > -1.8 V vs SCE).

Photocatalytic deaminative benzylation and alkylation of tetrahydroisoquinolines with N-alkylpyrydinium salts

A ruthenium-catalyzed photoredox coupling of substituted N-aryltetrahydroisoquinolines (THIQs) and different bench-stable pyridinium salts was successfully developed to give fast access to 1-benzyl-THIQs. Furthermore, secondary alkyl and allyl groups were also successfully introduced via the same method. Additionally, the typically applied N-phenyl group in the THIQ substrate could be replaced by the cleavable p-methoxyphenyl (PMP) group and successful N-deprotection was demonstrated.