1227479-70-0

Basic information

• Product Name: 5-hydroxy-3,7-dimethoxyflavanone
• Synonyms: 5-hydroxy-3,7-dimethoxyflavanone
• CAS NO: 1227479-70-0
• Molecular Weight: 300.311
• Mol File: 1227479-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-3,7-dimethoxyflavanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-3,7-dimethoxyflavanone(1227479-70-0)
• EPA Substance Registry System: 5-hydroxy-3,7-dimethoxyflavanone(1227479-70-0)

Safety Data

• Hazardous Substances Data: 1227479-70-0(Hazardous Substances Data)

Upstream product

• 70786-48-0 5-hydroxy-3,7-dimethoxyflavone 

Downstream Products

• 1227479-73-3 5-hydroxy-3,7-dimethoxyflavanone oxime 
• 1227479-75-5 4,5-dihydroxy-3,7-dimethoxyflavan 

Relevant articles and documents

Cytotoxicity against KB and NCI-H187 cell lines of modified flavonoids from Kaempferia parviflora

Flavones 1-4 isolated from Kaempferia parviflora were used for structural modification. Sixteen flavonoid derivatives, including four new derivatives, were synthesized and evaluated for cytotoxicity against KB and NCI-H187 cell lines. Flavanones 2a-4a demonstrated higher cytotoxic activity than the parent compounds. Cytotoxicity against KB cell line of oxime 1c was about 7 times higher than the ellipticine standard. Interestingly, oximes 1c and 2c exhibited highly potent cytotoxicity against NCI-H187 cell line with IC50 values of 0.014 and 0.23 μM, respectively. Oximes 4c and 5c showed strong cytotoxicity against NCI-H187 cell line with IC50 values of 4.04 and 2.32 μM, respectively.