1227743-95-4Relevant articles and documents
Selection, preparation, and evaluation of small-molecule inhibitors of toll-like receptor 4
Bevan, Douglas E.,Martinko, Alexander J.,Loram, Lisa C.,Stahl, Joshua A.,Taylor, Frederick R.,Joshee, Sampada,Watkins, Linda R.,Yin, Hang
, p. 194 - 198 (2010)
Toll-like receptor 4 (TLR4), a membrane-spanning receptor protein that functions in complex with its accessory protein MD-2, is an intriguing target for therapeutic development. Herein, we report the identification of a series of novel TLR4 inhibitors and