1228230-29-2Relevant articles and documents
Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT2C agonists for the treatment of metabolic disorders
Tye, Heather,Mueller, Stephan G.,Prestle, Juergen,Scheuerer, Stefan,Schindler, Marcus,Nosse, Bernd,Prevost, Natacha,Brown, Christopher J.,Heifetz, Alexander,Moeller, Clemens,Pedret-Dunn, Anna,Whittaker, Mark
, p. 34 - 37 (2011)
The discovery of a novel series of 5-HT2C agonists based on a tricyclic pyrazolopyrimidine scaffold is described. Compounds with good levels of in vitro potency and moderate to good levels of selectivity with respect to the 5-HT2A an