1228465-61-9

Basic information

• Product Name: N-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}phenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide
• Synonyms: N-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}phenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide
• CAS NO: 1228465-61-9
• Molecular Weight: 514.651
• Mol File: 1228465-61-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}phenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}phenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide(1228465-61-9)
• EPA Substance Registry System: N-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}phenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide(1228465-61-9)

Safety Data

• Hazardous Substances Data: 1228465-61-9(Hazardous Substances Data)

Upstream product

• 99-09-2 3-nitro-aniline 
• 4548-45-2 2-chloro-5-nitropyridine 
• 18437-64-4 tert-butyl (3-nitrophenyl)carbamate 
• 1228466-19-0 N-{5-[(3-aminophenyl)(methyl)amino][1,3]thiazolo[5,4-b]pyridin-2-yl}cyclopropanecarboxamide 
• 1943-67-5 4-(t-butyl)phenyl isocyanate 
• 528882-15-7 N-methyl-(3-nitrophenyl)carbamic acid tert-butyl ester 
• 528882-16-8 (3-amino-phenyl)-methyl-carbamic acid tert-butyl ester 
• 1228466-13-4 tert-butyl methyl{3-[(trifluoroacetyl)amino]phenyl}carbamate 
• 1228466-14-5 2,2,2-trifluoro-N-[3-(methylamino)phenyl]acetamide 
• 1228466-15-6 2,2,2-trifluoro-N-{3-[methyl(5-nitropyridin-2-yl)amino]phenyl}acetamide 
• 1228466-17-8 N-{3-[(2-amino[1,3]thiazolo[5,4-b]pyridin-5-yl)(methyl)amino]phenyl}-2,2,2-trifluoroacetamide 
• 1228531-94-9 N-[3-[(5-aminopyridin-2-yl)(methyl)amino]phenyl]-2,2,2-trifluoroacetamide 
• 1228466-18-9 N-[5-(methyl{3-[(trifluoroacetyl)amino]phenyl}amino)[1,3]thiazolo[5,4-b]pyridin-2-yl]cyclopropanecarboxamide 

Relevant articles and documents

HETEROCYCLIC COMPOUND AND USE THEREOF

A compound represented by formula (I) or a salt thereof, which has a potent Raf inhibitory activity. In formula (I), R1 represents an optionally substituted C1-6 alkyl, etc.; X represents —O— or —NR2— (wherein R2 represents a hydrogen atom or a C1-6 alkyl); Y represents a group represented by formula 2 (2ii or 2ii) (wherein ring A represents an optionally substituted benzene ring; Z represents a group represented by (1) —NR3CO—W1—, (2) —NR3CO—W1—O—, (3) —NR3CO—W1—O—W2—, (4) —NR3CO—W1—S—, (5) —NR3CO—W1—NR4—, (6) —NR3COO—, (7) —NR3COO—W1—, (8) —NR3CO—CO—, or (9) —NR3CONR4— (wherein R3 and R4 each represents a hydrogen atom, etc., and W1 and W2 each represents an optionally substituted C1-6 alkylene, etc.); and R5 represents an optionally substituted five- or six-membered ring group.