1228587-66-3

Basic information

• Product Name: [(6-amino-2-butoxy-5-nitro-pyrimidin-4-yl)-(4-pyrrolidin-1-ylmethyl-benzyl)amino]acetic acid ethyl ester
• Synonyms: [(6-amino-2-butoxy-5-nitro-pyrimidin-4-yl)-(4-pyrrolidin-1-ylmethyl-benzyl)amino]acetic acid ethyl ester
• CAS NO: 1228587-66-3
• Molecular Weight: 486.571
• Mol File: 1228587-66-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(6-amino-2-butoxy-5-nitro-pyrimidin-4-yl)-(4-pyrrolidin-1-ylmethyl-benzyl)amino]acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(6-amino-2-butoxy-5-nitro-pyrimidin-4-yl)-(4-pyrrolidin-1-ylmethyl-benzyl)amino]acetic acid ethyl ester(1228587-66-3)
• EPA Substance Registry System: [(6-amino-2-butoxy-5-nitro-pyrimidin-4-yl)-(4-pyrrolidin-1-ylmethyl-benzyl)amino]acetic acid ethyl ester(1228587-66-3)

Safety Data

• Hazardous Substances Data: 1228587-66-3(Hazardous Substances Data)

Upstream product

• 650628-72-1 4-[(pyrrolidin-1-yl)methyl]-benzaldehyde 
• 17201-43-3 4-cyanobenzyl bromide 
• 51359-78-5 4-(bromomethyl)benzaldehyde 
• 1228587-56-1 ethyl 2-((6-amino-2-(methylthio)-5-nitropyrimidin-4-yl)(3-(pyrrolidin-1-ylmethyl)benzyl)amino)acetate 
• 1228587-58-3 ethyl 2-(3-(pyrrolidin-1-ylmethyl)benzylamino)acetate 
• 91271-78-2 (3-(pyrrolidin-1-ylmethyl)phenyl)methanamine 

Downstream Products

• 1228586-25-1 C₂₂H₂₈N₆O₃ 
• 1228585-41-8 4-amino-2-n-butoxy-8-[4’-(pyrrolidin-1“-ylmethyl)-benzyl]-5,6,7,8-tetrahydropteridin-6-one 

Relevant articles and documents

METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS

The present invention provides methods of preparing 4-amino-2-biitoxy-8-(3- (pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and related compounds.

MODULATORS OF TOLL-LIKE RECEPTORS

Provided are modulators of TLRs of Formula II: pharmaceutically acceptable salts thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.