122874-85-5

Basic information

• Product Name: 1,2-Indolizinedicarboxylic acid, 5,6,7,8-tetrahydro-3-phenyl-, dimethyl ester
• CAS NO: 122874-85-5
• Molecular Formula: C18H19NO4
• Molecular Weight: 313.353
• Mol File: 122874-85-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2-Indolizinedicarboxylic acid, 5,6,7,8-tetrahydro-3-phenyl-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Indolizinedicarboxylic acid, 5,6,7,8-tetrahydro-3-phenyl-, dimethyl ester(122874-85-5)
• EPA Substance Registry System: 1,2-Indolizinedicarboxylic acid, 5,6,7,8-tetrahydro-3-phenyl-, dimethyl ester(122874-85-5)

Safety Data

• Hazardous Substances Data: 122874-85-5(Hazardous Substances Data)

Upstream product

• 144630-24-0 ethyl 3-(N-benzoylpiperidinyl)-3-oxopropanoate 
• 78348-46-6 N-benzoyl-2-piperidinecarboxylic acid 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 122874-83-3 ethyl 2-diazo-3-(N-benzoylpiperidinyl)-3-oxopropanoate 
• 2835-06-5 phenylglycin 
• 675-20-7 piperidin-2-one 
• 396129-93-4 α-phenyl-2-oxo-1-piperidineacetic acid 
• 122874-84-4 1-Oxo-5-phenyl-1,2,7,8,9,10-hexahydro-furo[3,2-i]indolizine-2,3a,4-tricarboxylic acid 2-ethyl ester 3a,4-dimethyl ester 

Relevant articles and documents

1,3-Dipolar cycloadditions of new mesoionic compounds. Synthesis of 1H-pyrrolo[1,2-c]thiazoles, pyrrolizines and 5,6,7,8-tetrahydroindolizines

We studied the 1,3-dipolar cycloaddition reactions between alkyne dipolarophiles and the new mesoionic compounds 2H,5H,7H-thiazolo[4,3-b]oxazol-2-one (12), 2H,5H,7H-pyrrolo[2,1-b]oxazol-2-one (13) and 2H,5H,7H-oxazolo[3,2-a]pyridin-2-one (14). These 1,3-dipoles were prepared in situ by means of cyclodehydration with acetic anhydride of the corresponding α-substituted 4-oxo-3-thiazolidine- (9), 2-oxo-1-pyrrolidine- (10) and 2-oxo-1-piperidineacetic acids (11). The cycloaddition reactions with alkyne dipolarophiles afforded single 1H-pyrrolo[1,2-c]thiazole, pyrrolizine and 5,6,7,8-tetrahydroindolizine derivatives, or a mixture of the two possible regioisomers, depending on whether symmetrical or unsymmetrical alkynes.

1,3-Dipole Cascade. A New Method for Azomethine Ylide Formation

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