122889-15-0Relevant articles and documents
Preparation of α-(N-Trimethylsilyl)imino Esters and Their Use ih the Synthesis of α-Amino Esters and 2-Alkoxycarbonylimidazol-4(2H)-ones
Matsuda, Yoshihiko,Tanimoto, Shigeo,Okamoto, Tadashi,Ali, Syed Mashhood
, p. 279 - 281 (2007/10/02)
The reaction of α-keto esters with lithium 1,1,1,3,3,3-hexamethyldisilazanide afforded α-(N-trimethylsilyl)imino esters in good yields, which were reduced to the corresponding α-amino esters by reducing agents such as NaBH3CN. α-(N-Trimethylsilyl)imino esters were treated with methanol to afford 2-alkoxycarbonylimidazole-4(2H)-ones via dimerization of the intermediate α-imino esters.
