122903-68-8 Usage
Description
FMOC-LYS(TEOC)-OH, also known as Fmoc-L-lysine(tetrahydrofuran-3-oxycarbonyl), is a synthetic compound derived from the amino acid L-lysine. It is characterized by its white crystalline powder form and is commonly used in the field of organic chemistry and biochemistry.
Uses
Used in Pharmaceutical Industry:
FMOC-LYS(TEOC)-OH is used as a reactant for the synthesis of synthetic substrate analogs of Escherichia coli MurG. This application is significant because it aids in the development of new drugs and therapies targeting bacterial infections, particularly those caused by E. coli.
Used in Organic Chemistry:
FMOC-LYS(TEOC)-OH is used as a building block in the synthesis of various organic compounds. Its unique structure allows for the creation of complex molecules with potential applications in different industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Biochemistry:
FMOC-LYS(TEOC)-OH is used as a reagent in the study of protein structure and function. Its incorporation into peptide sequences can help researchers understand the role of specific amino acids in protein folding, stability, and interactions with other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 122903-68-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,9,0 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 122903-68:
(8*1)+(7*2)+(6*2)+(5*9)+(4*0)+(3*3)+(2*6)+(1*8)=108
108 % 10 = 8
So 122903-68-8 is a valid CAS Registry Number.
122903-68-8Relevant articles and documents
Modular Total Synthesis of Farnesyl Analogues of Cell Wall Precursors Lipid i and II Containing the Staphylococcus aureus Pentaglycine Bridge Modification
Wingen, Lukas M.,Rausch, Marvin,Schneider, Tanja,Menche, Dirk
supporting information, p. 10206 - 10215 (2020/09/03)
A scalable and modular total synthesis of 3-lipid I and 3-lipid II was accomplished by a novel route involving an efficient solid phase synthesis of the peptide fragment and an effective chemoenzymatic attachment of the second sugar moiety. The generality of this route was further documented by the synthesis of an analogue bearing the pentaglycine interpeptidic bridge modification characteristic for the human pathogen Staphylococcus aureus.
The kinetic characterization of Escherichia coli MurG using synthetic substrate analogues
Ha, Sha,Chang, Emmanuel,Lo, Mei-Chu,Men, Hongbin,Park, Peter,Ge, Min,Walker, Suzanne
, p. 8415 - 8426 (2007/10/03)
Bacterial resistance to existing antibiotics poses a serious threat to human health. Because the peptidoglycan surrounding bacterial cells is essential for survival, the enzymes involved in peptidoglycan biosynthesis are attractive targets for the design