1229037-82-4

Basic information

• Product Name: benzyl oleanolate 3-O-2″,3″,4″,6″-tetra-O-benzoyl-β-D-glucopyranosyl-(1→2)-3′,4′-O-isopropylidene-α-L-arabinopyranoside
• Synonyms: benzyl oleanolate 3-O-2″,3″,4″,6″-tetra-O-benzoyl-β-D-glucopyranosyl-(1→2)-3′,4′-O-isopropylidene-α-L-arabinopyranoside
• CAS NO: 1229037-82-4
• Molecular Weight: 1297.59
• Mol File: 1229037-82-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl oleanolate 3-O-2″,3″,4″,6″-tetra-O-benzoyl-β-D-glucopyranosyl-(1→2)-3′,4′-O-isopropylidene-α-L-arabinopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl oleanolate 3-O-2″,3″,4″,6″-tetra-O-benzoyl-β-D-glucopyranosyl-(1→2)-3′,4′-O-isopropylidene-α-L-arabinopyranoside(1229037-82-4)
• EPA Substance Registry System: benzyl oleanolate 3-O-2″,3″,4″,6″-tetra-O-benzoyl-β-D-glucopyranosyl-(1→2)-3′,4′-O-isopropylidene-α-L-arabinopyranoside(1229037-82-4)

Safety Data

• Hazardous Substances Data: 1229037-82-4(Hazardous Substances Data)

Upstream product

• 875878-34-5 benzyl oleanolate 3-O-3′,4′-O-isopropylidene-α-L-arabinopyranoside 
• 149707-75-5 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 
• 149707-76-6 O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate 

Downstream Products

• 1229037-83-5 benzyl 3-O-[2-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oleanolate 

Relevant articles and documents

Synthesis and biological evaluation of Raddeanin A, a triterpene saponin isolated from Anemone raddeana

First, Raddeanin A, a cytotoxic oleanane-type triterpenoid saponin isolated from Anemone raddeana REGEL, was synthesized. Stepwise glycosylation was adopted in the synthesis from oleanolic acid, employing arabinosyl, glucosyl and rhamnosyl trichloroacetimidate as donors. The chemical structure of Raddeanin A was confirmed by means of 1H-NMR, 13C-NMR, IR, MS and elemental analysis, which elucidated the structure to be 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranoside oleanolic acid. Biological activity tests showed that in the range of low concentrations, Raddeanin A displayed moderate inhibitory activity against histone deacetylases (HDACs), indicating that the HDACs' inhibitory activity of Raddeanin A may contribute to its cytotoxicity.

Synthesis and α-glucosidase inhibitory activity of oleanolic acid derivatives

Glucosidations of oleanolic acid (1) and its dihydroxy-olide derivatives (2) were carried out to provide eight glycosides. All synthesized compounds were evaluated by in vitro α-glucosidase inhibitory activity assay. 3-Acetyl dihydroxy-olide oleanolic der