1229444-44-3 Usage
Description
1-Methyl-1-[4-(diphenylphosphino)benzyl]pyrrolidinium Bromide is a complex organic compound featuring a pyrrolidinium cation with a diphenylphosphino group attached to a benzyl moiety. This unique structure endows the molecule with specific chemical properties, making it a versatile and valuable compound in various chemical applications.
Uses
Used in Organic Synthesis:
1-Methyl-1-[4-(diphenylphosphino)benzyl]pyrrolidinium Bromide is used as a catalyst in organic synthesis for facilitating and enhancing the rate of chemical reactions. Its diphenylphosphino group provides a strong and selective catalytic effect, making it particularly useful in the formation of carbon-carbon and carbon-heteroatom bonds, as well as in various cross-coupling reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Methyl-1-[4-(diphenylphosphino)benzyl]pyrrolidinium Bromide is used as a catalyst for the synthesis of complex organic molecules, including those with potential therapeutic applications. Its ability to promote selective reactions and improve reaction yields can lead to the development of more efficient and cost-effective methods for producing pharmaceutical compounds.
Used in Chemical Research:
1-Methyl-1-[4-(diphenylphosphino)benzyl]pyrrolidinium Bromide is also utilized in chemical research as a tool for studying reaction mechanisms and exploring new synthetic pathways. Its unique structure and catalytic properties can provide valuable insights into the behavior of various organic substrates and help researchers develop innovative strategies for molecular synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1229444-44-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,9,4,4 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1229444-44:
(9*1)+(8*2)+(7*2)+(6*9)+(5*4)+(4*4)+(3*4)+(2*4)+(1*4)=153
153 % 10 = 3
So 1229444-44-3 is a valid CAS Registry Number.
1229444-44-3Relevant articles and documents
Wittig reaction with ion-supported Ph3P
Shimojuh, Naoya,Imura, Yumi,Moriyama, Katsuhiko,Togo, Hideo
experimental part, p. 951 - 957 (2011/03/18)
Ion-supported Ph3P, 4-(diphenylphosphino)benzyltrimethylammonium bromide A and N-methyl-N-[4-(diphenylphosphino)benzyl]pyrrolidinium bromide B, were used for the Wittig reaction. Ion-supported phosphonium salts A1 and B1, which were prepared from the reactions of ion-supported Ph3P A and B with ethyl bromoacetate, respectively, reacted with aromatic and aliphatic aldehydes in the presence of K2CO3 to give the corresponding α,β-unsaturated ethyl esters in good yields with high purity by simple filtration of the reaction mixture and subsequent removal of the solvent from the filtrate. Similarly, ion-supported phosphonium salts A2 and B2, which were prepared from the reactions of ion-supported Ph3P A and B with p-methylbenzyl bromide, respectively, reacted with aromatic and aliphatic aldehydes in the presence of NaH to provide the corresponding p-methylstyrene derivatives in good yields with high purity by simple filtration of the reaction mixture and the subsequent removal of the solvent from the filtrate. In both reactions, the co-product, ion-supported Ph3PO, could be obtained quantitatively by simple filtration, and was converted into the corresponding ion-supported Ph3P A and B again in high yields using dimethyl sulfate, followed by the reduction with LiAlH4. Recovered and regenerated ion-supported Ph3P A and B could be reused for the same Wittig reaction while maintaining good yields of ethyl (E)-3-(4′-chlorophenyl)-2-propenoate and 1-(4′-chlorophenyl)-2- (4″-methylphenyl)ethene with high purity by simple filtration and removal of the solvent from the filtrate.