1229606-73-8

Basic information

• Product Name: N-[4-[[4-[[[[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-1-naphthalenyl]oxy]-2-pyridinyl]-2-methoxyacetamide
• Synonyms: N-[4-[[4-[[[[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-1-naphthalenyl]oxy]-2-pyridinyl]-2-methoxyacetamide
• CAS NO: 1229606-73-8
• Molecular Weight: 578.671
• Mol File: 1229606-73-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[4-[[4-[[[[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-1-naphthalenyl]oxy]-2-pyridinyl]-2-methoxyacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-[[4-[[[[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-1-naphthalenyl]oxy]-2-pyridinyl]-2-methoxyacetamide(1229606-73-8)
• EPA Substance Registry System: N-[4-[[4-[[[[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-1-naphthalenyl]oxy]-2-pyridinyl]-2-methoxyacetamide(1229606-73-8)

Safety Data

• Hazardous Substances Data: 1229606-73-8(Hazardous Substances Data)

Upstream product

• 1229607-47-9 C₁₈H₂₁N₅O 
• 1229607-39-9 N-(4-((4-aminonaphthalen-1-yl)oxy)pyridin-2-yl)-2-methoxy acetamide 
• 1229607-40-2 2-methoxy-N-(4-(4-nitronaphthalen-1-yloxy)pyridin-2-yl)acetamide 
• 1229607-38-8 4-((4-nitronaphthalen-1-yl)oxy)pyridin-2-amine 
• 33631-05-9 2-amino-4-hydroxypyridine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 285984-25-0 3-tert-butyl-1-p-tolyl-1H-pyrazol-5-amine 
• 341-92-4 1-fluoro-4-nitronaphthalene 

Downstream Products

• 1337930-68-3 N-(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)-5,6,7,8-tetrahydronaphthalen-1-yloxy)pyridin-2-yl)-2-methoxyacetamide 

Relevant articles and documents

PYRAZOLE P38 MAP KINASE INHIBITORS

There are provided inter alia compounds of formula (I): wherein R1, R2a, R2b, R3, R4, L, X, R5 and R6 are as defined in the description for use in the treatment of inflammatory diseases.

P38 MAP KINASE INHIBITORS

The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes,particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD