1229612-63-8Relevant articles and documents
Design of new potent and selective secretory phospholipase A2 inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperaz
Meddad-Belhabich, Nadia,Aoun, Darina,Djimdé, Atimé,Redeuilh, Catherine,Dive, Georges,Massicot, France,Chau, Fran?ois,Heymans, Fran?oise,Lamouri, Aazdine
supporting information; experimental part, p. 3588 - 3600 (2010/08/05)
The group IIA human non-pancreatic secretory phospholipase A2 (hnp-sPLA2) is one of the enzymes implied in the inflammatory process. In the course of our work on inhibitors of this enzyme we investigated the influence of rigidity of