123004-53-5Relevant articles and documents
A stereoselective synthetic approach to N-alkyl-4β-methyl-5- phenylmorphans
Thomas, James B.,Gigstad, Kenneth M.,Fix, Scott E.,Burgess, Jason P.,Cooper, Julie B.,Mascarella, S. Wayne,Cantrell, Buddy E.,Zimmerman, Dennis M.,Carroll, F. Ivy
, p. 403 - 406 (2007/10/03)
A convergent, highly stereoselective synthetic approach to N-alkyl-4β- methyl-5-phenylmorphans has been developed utilizing alkylation of the metalloenamine of N-alkyl-1,2,3,6-tetrahydro-4-phenylpyridines with 2- (chloromethyl)-3,5-dioxahex-1-ene (Okahara's reagent) followed by Clemmensen reduction.