123016-21-7 Usage
Description
[S,(+)]-α-Methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid, also known as 6-MNA, is a chemical compound derived from naphthaleneacetic acid with demonstrated anti-inflammatory and analgesic properties. It has been recognized for its potent activity in animal models of pain and inflammation, making it a significant compound in the realm of pharmaceutical research and development.
Uses
Used in Pharmaceutical Industry:
6-MNA is used as a nonsteroidal anti-inflammatory drug (NSAID) for its ability to inhibit the synthesis of prostaglandins, which are chemical messengers that play a role in the body's inflammatory response. This application makes it a potential candidate for the treatment of conditions such as rheumatoid arthritis and osteoarthritis.
Used in Neuroprotective Applications:
6-MNA is also recognized for its antioxidant and neuroprotective effects, which contribute to its potential use in the development of treatments for neurological disorders and conditions where oxidative stress and neurodegeneration are factors.
Used in Research and Development:
As a compound with multiple potential applications, 6-MNA is used in the research and development of new pharmaceuticals and therapies, particularly in the fields of pain management, inflammation, and neuroprotection. Its study may lead to the discovery of novel treatments and a deeper understanding of the underlying mechanisms of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 123016-21-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,0,1 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 123016-21:
(8*1)+(7*2)+(6*3)+(5*0)+(4*1)+(3*6)+(2*2)+(1*1)=67
67 % 10 = 7
So 123016-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H19NO3/c1-15(23(25)26)17-6-7-19-13-21(11-9-18(19)12-17)27-14-20-10-8-16-4-2-3-5-22(16)24-20/h2-13,15H,14H2,1H3,(H,25,26)/t15-/m0/s1
123016-21-7Relevant articles and documents
Quinolinylmethoxy naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein R is hydrogen or lower alkyl; Y is STR2 or a pharmaceutically acceptable salt thereof, and its use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, in psoriasis, ulcerative colitis, rheumatoid arthritis as well as in other immediate hypersensitivity reactions.
Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein A is alkyl of 3-19 carbon atoms, diloweralkyl allyl, dihaloallyl, diphenylallyl, lower alkynyl, STR2 X is N or CR; Z is STR3 R is hydrogen or lower alkyl; R1 is hydrogen, lower alkyl or phenyl; R2 is hydrogen or loweralkyl; or R1 and R2 taken together form a benzene ring; and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, in psoriasis, ulcerative colitis, rheumatoid arthritis as well as in other immediate hypersensitivity reactions.
