123125-04-2Relevant articles and documents
Synthesis and Cardiotonic Activity of Novel Biimidazoles
Matthews, Donald P.,McCarthy, James R.,Whitten, Jeffrey P.,Kastner, Philip R.,Barney, Charlotte L.,et al.
, p. 317 - 327 (2007/10/02)
A series of substituted 2,2-bi-1H-imidazoles and related analogues was synthesized and evaluated for inotropic activity.Structure-activity relationship studies based on a nonclassical bioisosteric approach indicated the necessity of a cyano group on one o