123126-59-0

Basic information

• Product Name: Benzo[b]thiophene-2-sulfonamide
• Synonyms: benzothiophenesulfonamide;1-benzothiophene-2-sulfonamide;benzothiophene-2-sulfonamide;2-benzo[B]thiophenesulfonamide;Benzo[b]thiophene-2-sulfonic acid amide
• CAS NO: 123126-59-0
• Molecular Formula: C8H7NO2S2
• Molecular Weight: 213.281
• Mol File: 123126-59-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 201-202 °C
• Boiling Point: 432.6±37.0 °C(Predicted)
• Density: 1.502±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzo[b]thiophene-2-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene-2-sulfonamide(123126-59-0)
• EPA Substance Registry System: Benzo[b]thiophene-2-sulfonamide(123126-59-0)

Safety Data

• Hazardous Substances Data: 123126-59-0(Hazardous Substances Data)

Upstream product

• 90001-64-2 1-benzothiophene-2-sulfonyl chloride 
• 95-15-8 Benzo[b]thiophene 
• 1336-21-6 ammonium hydroxide 
• 7791-25-5 sulfuryl dichloride 

Downstream Products

• 190660-00-5 Benzo[b]thiophene-2-sulfonic acid 1-(4-chloro-phenylamino)-1-methylsulfanyl-meth-(Z)-ylideneamide 

Relevant articles and documents

Platelet ADP receptor inhibitors

Novel compounds of formulae (I) to (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof.

ANTITUMOR BENZOYLSULFONAMIDES

The present invention provides antitumor compounds of the formula (I); and antitumor methods.

Diarylsulfonylureas for use in treating secretory diarrhea

This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea. This invention also describes specific diarylsulfonylureas f