1231923-68-4

Basic information

• Product Name: N-(4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)phenyl)-5-(trifluoromethyl)pyridin-2-amine
• Synonyms: N-(4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)phenyl)-5-(trifluoromethyl)pyridin-2-amine
• CAS NO: 1231923-68-4
• Molecular Weight: 416.403
• Mol File: 1231923-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)phenyl)-5-(trifluoromethyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)phenyl)-5-(trifluoromethyl)pyridin-2-amine(1231923-68-4)
• EPA Substance Registry System: N-(4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)phenyl)-5-(trifluoromethyl)pyridin-2-amine(1231923-68-4)

Safety Data

• Hazardous Substances Data: 1231923-68-4(Hazardous Substances Data)

Upstream product

• 1227068-53-2 4-(3-(tetrahydro-2H-pyran-4-yl)pyrazin-2-yloxy)aniline 
• 69045-82-5 2-fluoro-5-(trifluoromethyl)pyridine 

Relevant articles and documents

AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS

Pyridine and pyrimidine compounds: or a pharmaceutically acceptable salt thereof, wherein m, n, R1, R2, R3, R4, R5, R6, R7, X1, X2, X3, X4, X5, X6, X7, X8, and Y are as defined in the specification; or a pharmaceutically acceptable salt thereof, wherein ring A, m, n, y, R2, R3, R4, R5, R6, R7, R8, R9, X1, X2, and ring A are as defined in the specification; and or a pharmaceutically acceptable salt thereof, wherein m, n, y, R2, R3, R4, R5, R6, R7, R9, X1, X2, and ring A are as defined in the specification; compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.