1232008-24-0

Basic information

• Product Name: C₂₂H₁₇N₅O₂S
• CAS NO: 1232008-24-0
• Molecular Weight: 415.475
• Mol File: 1232008-24-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₇N₅O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₇N₅O₂S(1232008-24-0)
• EPA Substance Registry System: C₂₂H₁₇N₅O₂S(1232008-24-0)

Safety Data

• Hazardous Substances Data: 1232008-24-0(Hazardous Substances Data)

Upstream product

• 18336-39-5 4-(1H-pyrazol-1-yl)benzene-1-sulfonyl chloride 
• 5805-39-0 2-(aminophenyl)benzimidazole 

Relevant articles and documents

From sensors to silencers: Quinoline- and benzimidazole-sulfonamides as inhibitors for zinc proteases

Derived from the extensive work in the area of small molecule zinc(II) ion sensors, chelating fragment libraries of quinoline- and benzimidazole- sulfonamides have been prepared and screened against several different zinc(II)-dependent matrix metalloproteinases (MMPs). The fragments show impressive inhibition of these metalloenzymes and preferences for different MMPs based on the nature of the chelating group. The findings show that focused chelator libraries are a powerful strategy for the discovery of lead fragments for metalloprotein inhibition.