123227-23-6 Usage
Molecular structure
A complex compound with a dibenzo[b,e]oxepine core and additional functional groups.
Carboxylic acid group
Contains a carboxylic acid functional group, which can form hydrogen bonds and participate in various chemical reactions.
Sulfanyl group
Contains a sulfanyl (-SH) group, which can form disulfide bonds and participate in redox reactions.
Methoxyphenylcarbonylaminoethyl group
Contains a 2-methoxyphenylcarbonylaminoethyl group, which adds complexity to the molecule and may influence its properties and potential applications.
Potential applications
May have potential pharmaceutical or industrial applications due to its unique structure and functional groups.
Further research needed
Specific uses and properties would need to be determined through further research and testing.
Hydrophobicity
The presence of the dibenzo[b,e]oxepine core and the methoxyphenyl group may contribute to the hydrophobic nature of the molecule.
Aromaticity
The dibenzo[b,e]oxepine core and the methoxyphenyl group are aromatic, which may influence the molecule's stability and reactivity.
Chirality
The molecule may contain chiral centers, which could result in different stereoisomers with distinct properties and potential applications.
Solubility
The presence of the carboxylic acid group may increase solubility in polar solvents, while the hydrophobic groups may decrease solubility in nonpolar solvents.
Reactivity
The presence of various functional groups may make the molecule reactive towards a range of reagents, depending on the specific reaction conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 123227-23-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,2,2 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 123227-23:
(8*1)+(7*2)+(6*3)+(5*2)+(4*2)+(3*7)+(2*2)+(1*3)=86
86 % 10 = 6
So 123227-23-6 is a valid CAS Registry Number.
123227-23-6Relevant articles and documents
Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1
Ohshima,Takami,Sato,Obase,Miki,Ishii,Karasawa,Kubo
, p. 3394 - 3402 (2007/10/02)
A series of 11-[[2-[(arylsulfonyl)amino]ethyl]thio]-6,11- dihydrodibenz[b,e]oxepin-2-carboxylic acids and related derivatives were synthesized. The compounds were tested for their antagonizing effects on guinea pig platelet TXA2/PGH2 receptors. Structure-activity relationships are discussed. (±)-11-[[2-[(Styrylsulfonyl)amino]ethyl]thio]-6,11- dihydrodibenz[b,e]oxepin-2-carboxylic acid (41) and (±)-11-[[2- [(phenylsulfonyl)amino]ethyl]thio]-6,11-dihydrodibenz[b,e]thiepin-2- carboxylic acid (4af) were the most promising compounds with K(i) values of 6.5 ± 0.29 and 3.7 ± 0.31 nM, respectively, for the TXA2/PGH2 receptor. These compounds also significantly inhibited U-46619-induced guinea pig platelet aggregation ex vivo (10 mg/kg po). Compound 41 was resolved into its optically active form. The (-)-isomer was 60-fold more potent than the (+)- isomer in the TXA2/PGH2 receptor binding assay. Some compounds tested in this study showed both TXA2/PGH2 receptor antagonizing and TXA2 synthase inhibitory effects.
