123331-32-8

Basic information

• Product Name: 4-Methyl-1-(phenylacetyl)imidazole
• CAS NO: 123331-32-8
• Molecular Weight: 200.24
• Mol File: 123331-32-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Methyl-1-(phenylacetyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-1-(phenylacetyl)imidazole(123331-32-8)
• EPA Substance Registry System: 4-Methyl-1-(phenylacetyl)imidazole(123331-32-8)

Safety Data

• Hazardous Substances Data: 123331-32-8(Hazardous Substances Data)

Upstream product

• 822-36-6 4-methyl-1H-imidazole 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 123331-45-3 Dimethyl 3-Methyl-7-phenylimidazo<1,2-a>pyridine-5,6-dicarboxylate 
• 123331-46-4 Dimethyl 2-Methyl-7-phenylimidazo<1,2-a>pyridine-5,6-dicarboxylate 

Relevant articles and documents

Regiospecific Synthesis, Structure, and Fluorescence Properties of Highly Substituted Imidazopyridines and Pyridobenzimidazoles

1-(Arylacetyl)imidazoles 1 react with acetylenedicarboxylic esters to provide highly functionalized imidazopyridines 2 in up to 89percent yield.The scope and limitations of this novel condensation reaction have been investigated, and a mechanistic interpretation is presented.A strong effect on the yield of this reaction is observed for electron-donating and electron-withdrawing substituents in the para position of the aryl ring.Moreover, the transformation is shown to proceed in a regiospecific manner starting with 4,5-unsymmetrically substituted 1-(arylacetyl)imidazoles (1d-g) and is extended to the synthesis of the corresponding pyridobenzimazoles 12.The crystal structure of derivative 2a has been determined by X-ray analysis.Imidazopyridines 2 and pyridobenzimidazoles 12, obtained by this procedure, are highly fluorescent in the visible region with characteristically large Stokes shifts.